The Yaiser Group

Research Scientist to Sr Research Scientist, Preformulation

How to Apply for this Job
Company: The Yaiser Group Contact Name: DICK YAISER Email your resume (Click Here) Use one of the above methods to apply for this job.

• Job ID:
• Date:06/27/2008
• Location:Mid-Southern Atlantic region
• State:Not Listed
• Current Professional Level:Experienced Staff Level
• Salary:Not Specified   Why?

Job Types:

Analytical Development/R&D Chemistry, Dosage Form Development/Formulation, Pre-Formulation

PREFORMULATION

Research Scientist to Sr Research Scientist, Preformulation Pharmaceutical Research and Development Description of Duties and Responsibilities: • Conduct fundamental physico-chemical characterization of small drug molecules including pH-solubility profile, pKa, partition coefficients, polymorphism/salt screening, solid and solution state stability studies, etc • Conduct drug-excipient compatibility and other relevant studies to provide active support to formulators in the formulation development process • Conduct mechanical and thermal property evaluation on API and formulations using MDSC, TGA, DMA, texture analyzer and DCA • Perform experiments to monitor physical form change during pharmaceutical processing • Conduct solubility and multi-media dissolution studies to support BCS and in vitro/in vivo correlation • Develop oral and IV formulations to support in vivo PK, TK and pharmacological studies in animals • Supervise chemists and /or Ph.D. scientist to conduct the above preformulation activities Requirements: • Ph.D. in Physical Organic Chemistry/Pharmaceutical Chemistry/ Medicinal Chemistry/Analytical Chemistry/Pharmaceutics with 0-5 years experience in preformulation • Fundamental knowledge of pharmaceutical product development is a must • Training in analytical techniques and instrumentation such as HPLC, LC/MS, DSC, TGA, FTIR, Hot-Stage Microscopy, Vapor Sorption, Isothermal Microcalorimetry, Particle Size Analysis and XRD is desirable • Expertise/Experience in thermal analytical testing is a plus • Knowledge of computer data sharing environment and a good understanding of formulations, especially solid dosage forms is necessary • Must be able to work in a team environment • Excellent verbal and written communication skills

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