The main focus of this position will be the application and development of techniques for studying the solution structures of proteins and protein/protein or protein/ligand complexes of therapeutic interest. In addition, the role may involve studies of biologically active peptides and small molecules with particular emphasis on determining their conformations. The protein NMR facilities include dedicated 800, 600, and 500 MHz spectrometers, Linux workstations, and fully equipped protein expression and purification labs. The NMR facility complements protein engineering, protein crystallography and modeling efforts within the Early Discovery Biochemistry and Structural Biology Departments. Highly motivated researchers, capable of independent work in a collaborative environment are sought for this position.
Who You Are
Applicants should have a Ph.D., at least one first author paper in a reputable journal and extensive practical experience. The applicant must also be familiar with the principles ad practice of protein NMR spectroscopy and protein structure determination. Molecular biology and/or protein chemistry expertise is highly advantageous.
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